Generation of an induced pluripotent stem cell line (FRIMOi002-A) from a retinitis pigmentosa patient carrying compound heterozygous mutations in USH2A gene.
Riera M, Patel A, Corcostegui B, Chang S, Corneo B, Sparrow JR, Pomares E. Establishment and characterization of an iPSC line (FRIMOi001-A) derived from a retinitis pigmentosa patient carrying PDE6A mutations. Riera M, Patel A, Corcostegui B, Chang S, Sparrow JR, Pomares E, Corneo B. Generation of two iPS cell lines (FRIMOi003-A and FRIMOi004-A) derived from Stargardt patients carrying ABCA4 compound heterozygous mutations. Riera M, Patel A, Burés-Jelstrup A, Corcostegui B, Chang S, Pomares E, Corneo B, Sparrow JR. Small molecules restore bestrophin-1 expression and function of both dominant and recessive bestrophinopathies in patient-derived RPE. Liu J, Taylor R.L., Baines R.A., Swanton L., Freeman S., Corneo B., Patel A., Marmorstein A., Knudsen T., Black G.C., Manson F. Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells. Garcia-Diaz A., Efe G., Kabra K, Patel A, Lowry E.R., Shneider N., Corneo B., Wichterle H. Establishment and characterization of two iPSC lines derived from healthy controls. Patel A, Diaz AG, Moore JC, Sirabella D & Corneo B. PMID: 34061592Īvior, Y., Ron, S., Kroitorou, D., Albeldas, C., Lerner, V., Corneo, B., Nitzan, E., Laifenfeld, D., Cohen Solal, T. Depression patient-derived cortical neurons reveal potential biomarkers for antidepressant response. Molecular features of the measles virus viral fusion complex that favor infection and spread in the brain. Mathieu C, Bovier F, Ferren M, Nicole Lieberman N, Predella C, Lalande A, Peddu V, Lin M, Addetia A, Patel A, Outlaw V, Corneo B, Dorrello N, Briese T, Hardie D, Horvat B, Moscona A, Greninger A, and Porotto M. Generation of the iPSC line CUIMCi003-A derived from a patient with severe early onset obesity. Iannello G, Patel A, Sirabella D, Corneo B, Thaker V. Cortical Overgrowth in a Preclinical Forebrain Organoid Model of CNTNAP2-Associated Autism Spectrum Disorder. Stem Cell Res. 2021 Dec 23 59:102635ĭe Jong J., Llapashtica C., Genestine M., Strauss K., Provenzano F., Sun Y., Zhu H., Cortese G., F Brundu F., Brigatti K., Corneo B, Migliori B., Tomer R., Kushner S., Kellendonk C., Javitch J., Xu B., and Markx S. Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL. Sigma non-opioid receptor 1 is a potential therapeutic target for long QT syndrome. Yamamoto, Amy Chalan, Risako Yang, Achchhe Patel, Dario Sirabella, Teresa M. Klein, Danielle Aina-Badejo, Kazushige Yoshida, Hannah E.
LouJin Song, Ramsey Bekdash, Kumi Morikawa, Jose R. Some equipment, including the picking hood, the Lonza Nucleofector 4D and the Life Technologies Neon, is available to users for rental. The Gene Editing section of the Stem Cell Core Facility provides various services, including insertion of transgene and targeted single nucleotide modifications. The Cell Production section of the Stem Cell Core Facility offers to its users maintenance and supply of human ESC/iPSC derivation and characterization of hiPSC from fibroblasts or blood and differentiation of human pluripotent stem cells into functional, mature, highly purified progeniesto (including neuronal, cardiac, retinal pigment epithelium, hepatic, pancreatic & skeletal muscle.) Gene Editing We are connected to Stem Cell COREdinates, a consortium of pluripotent stem cell-focused core facilities, which allows us to take advantage of the sharing of the most updated and efficient protocols, expertise, and reagents. Some reagents commonly used in stem cell labs, as mTeSR1 media and irradiated mouse embryonic fibroblasts, are also available at discounted prices for our users. The Stem Cell Core Facility also offers training sessions and informal interactions between scientists from multiple laboratories working on different stem cell models. To offer genome editing services for the generation of custom-designed cell lines.To give our users access to quality-controlled pluripotent stem cells and stem cell-derivatives prepared using standardized approaches.
The Columbia Stem Cell Core Facility has two primary aims: The Stem Cell Core Facility is a multi-center facility at Columbia University Irving Medical Center, created to help users take advantage of up-to-date resources in the stem cell field in a timely and cost-efficient way.
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